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Resveratrol delivery through a nanoemulgel system (RES-NEG)-treated DNCB AD-induced mice skin showed concentration-dependent (0.5%, 0.75% and 1% w/w) improvement in the skin, as indicated by lesion severity score [190]

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The transcription factor that ultimately increases the synthesis of proinflammatory proteins, including pro-IL-1, pro-IL-18, NLRP3, and caspase-1, is mostly governed by NF-B, which provides a significant amount of overall control (Shi et al